About the meeting

For more than 20 years, the Gene Transcription in Yeast meeting series biannually brings together researchers using yeast to study mechanisms of gene expression. Owing to the exceptional experimental accessibility of yeasts - in vivo and in vitro, in S. cerevisiae, S. pombe and other yeasts - the yeast community keeps generating both pioneering method development as well as new concepts that often inspired analogous discoveries in the metazoan/human system. The meeting traditionally covers all steps from chromatin to transcription to RNA processing, and integrates different approaches such as structural biology, biochemistry, genetics, cell biology, high-throughput, computational, systems and single-cell technologies. While this groundwork is maintained, there is also a special focus for each meeting. The subtitle “From single molecules to phase separation” reflects both a renewed attention to the individual molecule as well as the will to embrace the exciting discoveries on liquid-liquid phase separation (LLPS) mediating the compartmentalization of many cellular, including nuclear functions. Invited speakers will talk about the discovery, function and biophysics of LLPS and the intrinsically disordered proteins involved in their formation. They will cover single molecule analyses including structural studies and systems biology will bring a quantitative flavor to the many genome-wide studies also dealing with the co-existence of concurrent machineries (e.g. replication) on the DNA. Importantly, talks selected from submitted abstracts and posters presented in prominent and extensive sessions contribute a wealth of cutting-edge research from the vibrant yeast community.

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About the meeting

Image courtesy of:
Tineke Lenstra: movie of transcription factor binding (red) to a transcription site (green);
Geeta Narlikar: Swi6-chromatin droplet (Designed by Serena Sanulli and drawn by @drawinscience)
Alex Holehouse: Structure of Gcn4 DNA binding and transactivation domains

Job Market

Do you have open positions or you are looking for one ?

Advertise your offer here: #jobmarket

Organizers

Domenico Libri

Institut Jacques Monod , CNRS, Université de Paris, France , domenico.libri@ijm.fr

Philipp Korber

Ludwig-Maximilians-Universität Munich, Germany, pkorber@lmu.de

speakers

Madan Babu

MRC Laboratory of Molecular Biology, Cambridge, UK, madanm@mrc-lmb.cam.ac.uk

Francois Bachand

Université de Sherbrooke, CA, f.bachand@USherbrooke.ca

Jean Beggs

Wellcome Trust Centre for Cell Biology University of Edinburgh, J.Beggs@ed.ac.uk

Steven Buratowski

Harvard Medical School, Boston, USA, steve_buratowski@hms.harvard.edu

Ana Casanal

MRC Laboratory of Molecular Biology, Cambridge, UK, acasanal@mrc-lmb.cam.ac.uk

Patrick Cramer

Max Planck Institute for Biophysical Chemistry, Goettingen, Germany, patrick.cramer@mpibpc.mpg.de

Xavier Darzacq

University of California, Berkeley, Darzacq Lab - darzacq@berkeley.edu

Eulalia de Nadal

Institute for Research in Biomedicine Parc Científic de Barcelona - eulalia.nadal@irbbarcelona.org

Sebastian Eustermann

EMBL Heidelberg, Germany, sebastian.eustermann@embl.de

Vincent Géli

Centre de Recherche en Cancerologie de Marseille (CRCM) - (CNRS / Inserm / Aix-Marseille Université / Institut Paoli et Calmettes) - vincent.geli@inserm.fr

Steve Hahn

Fred Hutchinson Cancer Research Center, Seattle, USA, shahn@fredhutch.org

Alex Holehouse

Washington University School of Medicine, USA, alex.holehouse@wustl.edu

Michael Keogh

Epicypher, Durham NC, USA, mkeogh@epicypher.com

Edda Klipp

Humboldt-Universität zu Berlin, Germany, edda.klipp@rz.hu-berlin.de

Tineke Lenstra

The Netherlands Cancer Institute, Amsterdam The Netherlands, t.lenstra@nki.nl

Samuel Marguerat

MRC London Institute of Medical Sciences, London, UK, samuel.marguerat@lms.mrc.ac.uk

Jane Mellor

University of Oxford, Oxford, UK, jane.mellor@bioch.ox.ac.uk

Geeta Narlikar

University of California at San Francisco School of Medicine, Geeta.Narlikar@ucsf.edu

B. Franklin Pugh

Cornell University, Ithaca, NY, fp265@cornell.edu

Marta Radman-Livaja

Institut de Génétique Moléculaire de Montpellier, France, marta.radman-livaja@igmm.cnrs.fr

David Shore

University of Geneva, Switzerland, David.Shore@unige.ch

Susana Navarro Rodriguez

Instituto de Biomedicina de Valencia, Spain, srodriguez@ibv.csic.es

Kevin Struhl

Harvard Medical School, Boston, USA, kevin@hms.harvard.edu

Lars Steinmetz

EMBL Heidelberg, Germany; Stanford University, USA; Lars.Steinmetz@stanford.edu

Francoise Stutz

University of Geneva, Switzerland, Francoise.Stutz@unige.ch

David Tollervey

Wellcome Centre for Cell Biology, University of Edinburgh, UK, d.tollervey@ed.ac.uk

Lidia Vasilieva

University of Oxford, UK, lidia.vasilieva@bioch.ox.ac.uk

Program - to be announced

...

Important dates

Registration Opening

February 10th 2020

Registration Deadline

April 15th 2020

Abstract Deadline

April 15th 2020

Acceptance notification

May 1st 2020

Payment Deadline

May 15th 2020

Up to 130 participants will be accepted. Selection will be based on abstract. A number of abstracts will be selected for oral presentation

Registration includes

  • bus transfer from and to Barcelona airport (on scheduled times only)

  • accomodation in twin occupancy rooms

  • all meals

  • half day excursion

  • abstract book

Registration fees

Academic, double occupancy

620€

Academic, single occupancy

820€

Industry, single occupancy

1000€

Transportation

There are daily flights from all international airports to  Barcelona  (120 km). A closer airport is Girona (30 km).

Bus shuttles from and to the Barcelona airport will be organized. There will be three shuttle buses on June 13th leaving Barcelona at 14h, 15h30 and 16h30.

Two buses will be leaving Sant Feliu going to Barcelona airport on June 18th after the last session (estimated arrival time 14h15).

For participants who cannot use the hotel shuttle,  line buses from the Sarfa company are also available from Barcelona to San Feliu de Guixols. Travel time is approximately two hours.

From Barcelona take exit N° 9 on the motorway A-7. From France take exit N° 7.

The nearest train station is Girona (30 km). A taxi from the train station to Sant Feliu costs approximately 35€.

The venue

Hotel Eden Roc, 17220 Sant Feliu de Guixols, Girona, Spain, Email: edenroc@caproig.com, tel +34 972 320100

The Hotel Eden Roc is located 120km northeast of Barcelona at the Costa Brava, about 1km from San Feliu de Guixols, in an unrivalled and peaceful peninsula

Map

Job Market

We can advertise your offer here, and you meet in Sant Feliu !

  • Do you have a post-doc or PhD position open ? Send us a few lines and a link to your ad !

  • Are you looking for a post-doc position ? Send us a few lines with your interests and a link to your CV !

The research group of Dr. Kurt Schmoller at the Helmholtz Zentrum München (Institute of Functional Epigenetics) is looking for a PhD student and a Post-Doc

Download the offer here. For more information go to:

https://www.helmholtz-muenchen.de/ife/research/kurt-schmoller-cell-and-organelle-size-control/research/index.html

Libri Lab: We are looking for a dynamic and enthusiastic post-doc ready to share with us the thrill of understanding the fundamental mechanisms underlying gene expression and genome maintenance.

Download the offer here:                                   Contact: domenico.libri@ijm.fr

What  participants said about the 2018 meeting

Talks:

  • One of the best meetings I regularly attend
  • This meeting does a fantastic job covering all the different levels of transcription and gene expression studies: single molecule microscopy, structural biology, genomics, system biology, and many others. Yeast is unique in that all of these approaches can be used and integrated in a way that is simply impossible in mammalian cells, even in this age of CRISPR.
  • One of the most interesting meetings
  • This meeting had an especially well-balanced blend of topics ranging from the chromatin template to all levels of RNA biology, i.e., transcription, RNA processing, RNA export, and RNA degradation.
  • It was a formidable conference covering the hottest topics of the field.
  • Plenty of non published data
  • I was very impressed that most people presented unpublished data.
  • I took 30 pages of notes during the meeting. Just today during the departmental seminar of myhome institution, I gave a short meeting report and could not even remotely cover all the new and relevant information. The majority of presentations covered so far unpublished data.
  • Plenty of new information and mehtods.
  • The conference was extremely enriching, presenting the new advances in the field, for many of them ahead of publication (many papers available in BioRxiv before publication in journal).

Posters:

  • Poster session was excellent. Organizer provide us full opportunity and time to explain our research to other researchers. Time we spends with researchers was excellent
  • Great organization and plenty of time to see posters and talk with the scientis
  • The scientific quality of the posters was mainly very high. It was great to have posters related to the oral presentations. So we could follow up on topics that were raised already and got further Information. It was very good that poster sessions were in the evening with an « open end ».
  • There was ample time for discussions and meeting all the participants. Indeed, the attendance to the poster sessions was very high. PhD students were excited to discuss their projects with other PIs, and PIs got into more detailed discussions than was possible during the questions after the talk.

Networking:

  • This is excellent for research. We met many young researchers and discuss the research and possibilities of future project collaborations.
  • At the previous workshop in 2016, I made a new contact and we started a collaboration. I presented results from this collaboration in my lecture and discussed ongoing experiments with him. This very interesting project would not have started if we had not met at the last workshop. At the latest workshop I again made a new contact who has proposed a collaboration.
  • My lab is just going into a new direction involving R-Loops and at the meeting I could talk at length with two of the well-known experts in this field right away. We are still in contact and the first plasmid that we need in this regard is already underway by FedEx. The community at this meeting is extremely helpful. People are very accessible and as everyone works with the same model system, the exchange of reagents and protocols is excellent and fast.
  • This workshop is excellent to meet new people. The combination of venue and program « forces » people to interact
  • Many collaborations set up and critical info gained for ongoing challenging approaches
  • Thanks to this meeting i was able to find a eventual lab for my post doc.
  • Probably the most useful part of this meeting is the networking

The venue:

  • Awesome Place. I want to attend same conference if it will schedule in future
  • Excellent location with just enough isolation from the surroundings to keep everyone nearby and foster a sense of community.
  • The location is delightful, the accommodation and food were excellent (the weather was not, but that didn’t matter). Access to the hotel was problematic due to extensive construction works but that is temporary.
  • The conference room was perfect. We never had to wait for meals or coffee. The rooms were very good.
  • Very nice venue, with the hotel and the lecture hall at the same location. This means that there is no time wasted on traveling to and from the venue and therefore much more time to talk /discuss with others.
  • The location was spectacular – a bit isolated but in a good way to balance both work and relaxation during down time
  • Ideal place as all speakers are accessible in the venue and do not leave. That is key to start new interactions.
  • The atmosphere of this place is amazing, it is very easy to get contact with differentpeople (PhD-students, post-docs, PIs).